Toxoplasma gondii rhoptry discharge factor 3 is essential for invasion and microtubule-associated vesicle biogenesis.

Rhoptries are specialized secretory organelles conserved across the Apicomplexa phylum, essential for host cell invasion and critical for subverting of host cellular and immune functions.They contain proteins and membranous materials injected directly into the host cells, participating in parasitophorous vacuole formation.Toxoplasma Glass Drop Down

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How does the import of environmental intermediate goods affect CO2 emissions? theoretical and empirical research of prefecture-level cities of China

This paper constructs a theoretical model of biased production decisions due to the import of environmental intermediate goods.Additionally, it analyzes the influence of these imports on CO2 emissions based on the trade and CO2 emission data of Chinese ARGININE prefecture-level cities from 2000 to 2016.Furthermore, it empirically explores how envir

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Immune checkpoint inhibitors as the second-line treatment for advanced esophageal squamous cell carcinoma: a cost-effectiveness analysis based on network meta-analysis

Abstract Background Immune checkpoint inhibitors (ICIs) have demonstrated superior clinical efficacy in prolonging overall survival (OS) as the second-line treatment for advanced or metastatic esophageal squamous cell carcinoma (ESCC), and were recommended by the guidelines.However, it remains uncertain which ICI is the most cost-effective.This stu

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